l-type ca2 channel — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8674	SR33805		Calcium Channel
	SR33805 is a potent antagonist of Ca2+ channel(EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively)		Calcium Channel
T0957	Isradipine	PN 200-110	Calcium Channel , Autophagy
	Isradipine (PN 200-110) is a dihydropyridine calcium channel blockers with antihypertensive and vasodilator activities. Isradipine blocks the calcium entry through the calcium ion channels of coronary and peripheral vasc...		Calcium Channel , Autophagy
T0145	Felodipine	CGH-869	Calcium Channel , Autophagy
	Felodipine (CGH-869) is a longlasting 1, 4-dihydropyridine calcium channel repressor.		Calcium Channel , Autophagy
T1101	Minocycline hydrochloride	Minocycline HCl	HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
	Minocycline hydrochloride (Minocycline HCl) is a tetracycline antibiotic with excellent absorption and tissue penetration that is used for several bacterial infections as well as treatment of acne. Minocycline hydrochlor...		HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
T6777	Bay K 8644	(±)-BAY-K-8644,SQ 28,873	Calcium Channel
	Bay K 8644 (SQ 28,873) is a potent, selective activator of L-type Ca2+ channel with IC50 of 17.3 nM.		Calcium Channel
T12032	Mibefradil dihydrochloride	Ro 40-5967 (dihydrochloride)	Calcium Channel
	Mibefradil dihydrochloride (Ro 40-5967 (dihydrochloride)) is an blocker of calcium channel with moderate selectivity for T-type Ca2+ channels (T-type and L-type currents with IC50s of 2.7 μM and 18.6 μM, respectively).		Calcium Channel
T23301	(S)-(+)-Niguldipine hydrochloride		Others
	(S)-(+)-Niguldipine hydrochloride is a L-type Ca2+ channel blocker and α1A-adrenoceptor antagonist.		Others
TQ0144	(S)-(-)-Bay-K-8644	(S)-(-)-Bay K 8644	Calcium Channel
	(S)-(-)-Bay-K-8644 ((S)-(-)-Bay K 8644) is an agonist of L-type Ca2+ channel and activates Ba2+ currents with an EC50 of 32 nM.		Calcium Channel
T0388	Cilnidipine	FRC-8653	Calcium Channel
	Cilnidipine (FRC-8653)(FRC8653) is a dual L- and N-type calcium channel blocker and displays antihypertensive, sympatholytic and neuroprotective activity.		Calcium Channel
T2782L	Catharanthine Tartrate(2468-21-5(free base))		Calcium Channel
	Catharanthine Tartrate is a natural product isolated from Madagascar periwinkle, Catharanthine Tartrate inhibits voltage-operated L-type Ca2+ channel, with anti-cancer and blood pressure-lowering activity		Calcium Channel
T15301	Fluspirilene	Redeptin,R 6218	Calcium Channel
	Fluspirilene (R 6218) is a non-competitive L-type calcium channel antagonist (IC50: 0.03 μM).Fluspirilene is a long-acting antipsychotic compound used in the treatment of schizophrenia.		Calcium Channel
TQ0153	Mibefradil	Ro 40-5967	Calcium Channel
	Mibefradil is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s: 2.7 μM and 18.6 μM for T-type and L-type currents).		Calcium Channel
T23225	(R)-(-)-Niguldipine hydrochloride		Others
	(R)-(-)-Niguldipine hydrochloride is a L-type Ca2+ channel blocker and α1A-adrenoceptor antagonist.		Others
T28489	R-(-)-Niguldipine hydrochloride
	R-(-)-Niguldipine hydrochloride is a L-type Ca2+ channel blocker; potassium agonist that activates Ca2+-activated maxi K-channel; alpha1A-adrenoceptor antagonist; antihypertensive agent; Less active enantiomer.
T70036	AJG-049 HCl
	AJG-049 HCl is a calcium channel antagonist that inhibits L-type Ca2+ channels via diltiazem-binding site(s).
T70037	AJG-049 free base
	AJG-049 free base is a calcium channel antagonist that inhibits L-type Ca2+ channels via diltiazem-binding site(s).
T80496	Kurtoxin		Calcium Channel
	Kurtoxin is a selective Cav3 (T-type) voltage-gated Ca2+ channel gating inhibitor, exhibiting a dissociation constant (Kd) of 15 nM for the Cav3.1 (α1G T-type) Ca2+ channel. The compound demonstrates high-affinity intera...		Calcium Channel
T78066	BBT		Calcium Channel
	BBT enhances glucose-stimulated insulin secretion (GSIS) in compromised conditions, demonstrates anti-hyperglycemia effects, and shields β-cells from cytokine- or streptozotocin (STZ)-triggered apoptosis in type 2 diabet...		Calcium Channel
T36803	AAQ chloride
	Photoswitchable Kv channel blocker (IC50 values are 2 and 64 μM at 500 nm and 380 nm respectively). Switches conformation from cis to trans at 500 nm and trans to cis at 380 nm. Exhibits minimal activity at Nav1.2 and L-...
T80078	Calciseptin		Calcium Channel
	Calciseptine, a neurotoxin isolated from the Black Mamba (Dendroaspis p. polylepis) venom, comprises 60 amino acids and is stabilized by four disulfide bonds. It specifically targets and blocks L-type calcium channels [1...		Calcium Channel